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Lincomycin was not found to be mutagenic in the Ames Salmonella reversion assay or the V79 Chinese hamster lung cells at the HGPRT locusIt did not induce DNA strand breaks in V79 Chinese hamster lung cells as measured by alkaline elution or chromosomal abnormalities in cultured human lymphocytesIn vivolincomycin was negative in both the rat and mouse micronucleus assays and it did not induce sex-linked recessive lethal mutations in the offspring of male DrosophilaHoweverlincomycin did cause unscheduled DNA syntheses in freshly isolated rat hepatocytes.
Lincomycin is a lincosamide antibiotic that comes from the yeast Streptomyces lincolnensisLincomycin has been shown to be active in vitro against the following microorganismsAerobic gram-positive cocciStreptococcus pyogenes and Viridans group streptococciAerobic gram-positive bacilliCorynebacterium diphtheriaeAnaerobic gram-positive non-sporeforming bacilliPropionibacterium acnesAnaerobic gram-positive sporeforming bacilliClostridium tetani and Clostridium perfringens
Upset stomach or throwing upLoose stoolsdiarrheaStomach painDizzinessHeadacheFeeling sleepyIrritation where the shot is given.
The preservative benzyl alcohol has been associated with serious adverse eventsincluding thegasping syndromeand death in pediatric patientsAlthough normal therapeutic doses of this product ordinarily deliver amounts of benzyl alcohol that are substantially lower than those reported in association with thegasping syndromethe minimum amount of benzyl alcohol at which toxicity may occur is not knownThe risk of benzyl alcohol toxicity depends on the quantity administered and the liver and kidneyscapacity to detoxify the chemicalPremature and low-birth weight infants may be more likely to develop toxicity.
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lincocin works by killing or stopping the growth of bacteria causing your infection.
