In a clinical trial of bupropion immediate-release in mdd subjects with stable congestive heart failure n 36 , bupropion was associated with an exacerbation of pre-existing hypertension in 2 patients, leading to discontinuation of bupropion treatment.
Information about Bupropion.
HIV drugssuch as ritonavirlopinaviror efavirenzIf you use one of these drugs with bupropionyour doctor may increase your bupropion dosageAnti-seizure drugssuch as carbamazepinephenobarbitalor phenytoinIf you use one of these drugs with bupropionyour doctor may increase your bupropion dosage.
Initiate treatment in the autumn prior to onset of seasonal depressive symptoms and continue through the winter season.
This prescription medication may also be used as a treatment to manage attention deficit hyperactivity disorderADHDIt may also be used as a prescription treatment to help people quit smoking by decreasing cravings and nicotine withdrawal effectsIt may be used to prevent autumn-winter seasonal depressionseasonal affective disorderThis drug may also be used with other medications as a treatment for bipolar disorderdepression phaseIt may also be used to treat anxiety in people with depression.
Screen patients for bipolar disorder and monitor for these symptomsmay precipitate manichypomanic or mixed episodes in patients with bipolar disorder.
Assess blood pressure before initiating treatment with sustained release formulationand monitor periodically during treatmentrisk of hypertension is increased if sustained release formulation is used concomitantly with MAOIs or other drugs that increase dopaminergic or noradrenergic activityuse caution in patients with cardiovascular disease.
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a 2007 study published in the journal of clinical psychiatry investigated the combination of the drug zonisamide, approved only for seizure disorder treatment, and bupropion.