Methotrexate should be used only in life threatening neoplastic diseases, or in patients with psoriasis or rheumatoid arthritis with severe, recalcitrant, disabling disease which is not adequately responsive to other forms of therapy.
Information about Methotrexate.
Methotrexate can make you more likely to get infections or may worsen any current infectionsThereforewash your hands well to prevent the spread of infectionAvoid contact with people who have infections that may spread to otherssuch as chickenpoxmeaslesfluConsult your doctor if you have been exposed to an infection or for more details.
This medication may make you more sensitive to the sunLimit your time in the sunAvoid tanning booths and sunlampsUse sunscreen and wear protective clothing when outdoorsTell your doctor right away if you get sunburned or have skin blisters/redness.
In rare instancesthis drug may also cause liver problems when it is used for long periods of timeIf you are using methotrexate long terma liver biopsy is usually recommended.
If you are a manuse a condom to keep from causing a pregnancy while you are using methotrexateContinue using condoms for at least 3 months after your last dose.
Methotrexate has caused birth defects and death in unborn babiesWomen must avoid becoming pregnant while taking this medicationPregnant women who have psoriasis or rheumatoid arthritis must not use methotrexateSee also Precautions section
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concurrent use of pemetrexed and methotrexate is unlikely, however, the combination should be avoided.
