Hepatitis b patients who switch to cheaper lamivudine epivir-hbv after achieving undetectable hbv viral load and normal alt on entecavir baraclude are more likely to experience viral rebound.
Information about Epivir-HBV.
Reduction of the dosage of Epivir-HBV is recommended for patients with impaired renal functionsee Dosage and Administration2.4Clinical Pharmacology12.3
Geriatric patients are more likely to have decreased renal function and may require dose reduction and special monitoringClinical studies of Epivir-HBV did not contain significant numbers of elderly patients to determine if they would respond differently from younger patients.
Risk of immune reconstitution syndrome if used in combination with other antiretroviral drugs.
Lactic acidosis and steatosissee Warnings and Precautions5.1posttreatment exacerbations of hepatitissee Warnings and Precautions5.2pancreatitis.
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