Moore s anterior and abnormal foreigners along, heterogeneous joints of membrane, colchicine over the counter in canada and quantity, must partially awake and set in effect.
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This medication is used to prevent or treat gout attacksflaresUsually gout symptoms develop suddenly and involve only one or a few jointsThe big toekneeor ankle joints are most often affectedGout is caused by too much uric acid in the bloodWhen uric acid levels in the blood are too highthe uric acid may form hard crystals in your jointsColchicine works by decreasing swelling and lessening the build up of uric acid crystals that cause pain in the affected joint(s
Colchicine is a substrate of the efflux transporter P-glycoproteinP-gpand the CYP3A4 metabolizing enzymeFatal drug interactions have been reported when colchicine is administered with clarithromycina dual inhibitor of CYP3A4 and P-glycoproteinToxicities have also been reported when colchicine is administered with inhibitors of CYP3A4 that may not be potent inhibitors of P-gpe.ggrapefruit juiceerythromycinverapamilor inhibitors of P-gp that may not be potent inhibitors of CYP3A4e.gcyclosporine
Limitations of useThe safety and effectiveness of colchicine capsules for acute treatment of gout flares during prophylaxis has not been studied.
Taking certain medicines with colchicine capsules can cause your level of colchicine to be too highespecially if you have kidney or liver problemsTell your healthcare provider about all your medical conditionsincluding if you have kidney or liver problemsYour dose of colchicine capsules may need to be changedEven medicines that you take for a short period of timesuch as antibioticscan interact with colchicine capsules and cause serious side effects or death.
Colchicine is used to treat the symptoms of gout or familial Mediterranean feverFamilial Mediterranean fever is passed down in familiesIt can cause inflammationpain and swellingin the jointslungsor abdomenstomach area
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serious drug interactions can occur when certain medicines are used together with colchicine.