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Treatment with SARAFEM and any concomitant serotonergic agentsshould be discontinued immediately if the above events occur and supportive symptomatic treatment should be initiated.
During or within 14 days of MAOIsdo not start an MAOI during or within 5 weeks of fluoxetineConcomitant pimozidethioridazinelinezolidIV methylene blue.
The potential for interaction by a variety of mechanismsfor examplepharmacodynamicpharmacokinetic drug inhibition or enhancementetcis a possibility.
If the decision has been made to discontinue treatmentmedication should be taperedas rapidly as is feasiblebut with recognition that abrupt discontinuation can be associated with certain symptomssee Discontinuation of Treatment
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