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If you are also taking a beta-blockersuch as BetapaceCoregCorgardDutoprolInderalInnoPranLopressorNormodyneTenorminTenoreticToprolTrandateand othersdo not suddenly stop using the beta blocker without first talking to your doctorYou may need to use less and less before you stop the medication completelyStopping a beta blocker too quickly can cause serious heart problems that will not be prevented by nifedipine.
Patients recently withdrawn from beta blockers may develop a withdrawal syndrome with increased anginaprobably related to increased sensitivity to catecholaminesInitiation of Procardia treatment will not prevent this occurrence and might be expected to exacerbate it by provoking reflex catecholamine releaseThere have been occasional reports of increased angina in a setting of beta blocker withdrawal and Procardia initiationIt is important to taper beta blockers if possiblerather than stopping them abruptly before beginning Procardia.
If you have an allergy to nifedipine or any other part of Procardianifedipine capsulesIf you are allergic to any drugs like this oneany other drugsfoodsor other substancesTell your doctor about the allergy and what signs you hadlike rashhivesitchingshortness of breathwheezingcoughswelling of facelipstongueor throator any other signsIf you are taking any of these drugsCarbamazepinephenobarbitalphenytoinrifabutinrifampinor StJohn’s wortIf you have had a recent heart attackIf you are breast-feeding or plan to breast-feed.
Kidney diseaseliver diseaseespecially cirrhosisdiverticulitisinflammatory bowel diseasechronic constipationgastroesophageal reflux diseaseGERDor slow digestiona blockage in your digestive tractstomach or intestinesa colostomy or history of stomach surgery such as gastric bypasscolon cancerunderactive thyroiddiabetescoronary artery diseaseor congestive heart failure.
Other medications can affect the removal of nifedipine from your bodywhich may affect how nifedipine worksExamples include apalutamidecimetidineenzalutamideStJohn’s wortrifamycinssuch as rifabutinrifampindrugs used to treat seizuressuch as carbamazepinephenytoinamong others.
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